pydnameth

DNA Methylation Analysis Package

Authors: Yusipov Igor, Kalyakulina Alena, Timakin Nikita, Soluyanov Alexey

This package provides some pipelines for analysis of methylation data. The main goal is to find correlations between methylation on the one hand, and age, sex, disease, and other characteristics of subjects on the other hand.

Examples of free-access methylation datasets:

• GSE40279

• GSE87571

Documentation

Available at https://pydnameth.readthedocs.io.

Features

• Defining best age-predictors CpGs for different subjects subsets.

• Defining best observable-specic CpGs (sex-specific, disease-specific) which are differently methylated with age.

• Building Epigenetic Clock.

• Plotting subjects distribution depending on the observable (sex, disease).

• Plotting methylation profiles for CpGs.

Copyrights

Free software: MIT license